Your business development partner and strategic advisor

BioPharma Capital, LLC provides life sciences focused strategic and financial advisory services, including M&A advisory, strategic partnering and transaction process management.

We are dedicated to maximizing value for our clients using credible scientific and evidence driven approaches. Our clients are typically pharmaceutical and biotech companies considering partnering, out-licensing, divestitures, fund raising or corporate sales.

Our team provides decades of experience in transaction support, healthcare strategy consulting, pricing and market access, forecasting, investment banking and translational research. We understand the science and technology behind the assets we represent and we have vast expertise managing transactions.

Strategy and negotiation for transformative life science transactions

We run disciplined sell-side processes for biotech and pharma assets. We identify the right buyers and partners, position your program against their priorities, and manage outreach so it creates real competitive tension.

Our positioning rests on rigorous analysis: a composite valuation built from multiple secondary sources and backed by more than 1,000 primary research interviews with clinicians, payers, and experts across the US and EU. That depth lets us defend value and structure terms that capture it.

Numbers alone don’t close deals. Process does. We keep timelines moving, handle multiple bidders, and negotiate firmly at the table. We stay with you from first outreach through signing, so the final terms reflect the full value of your asset or company.

We are dedicated to creating value for life science companies

We specialize exclusively in life sciences strategic advisory and transaction services. Our clients have included 15 of the top 20 pharma/biotech companies and dozens of small and mid-size biotech and spec pharma companies. We have experience working across all stages of the product lifecycle, from research collaborations and lead identification to in-line growth strategies and lifecycle planning.

Partner with us to provide strategic direction and drive towards optimal transactions

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Our Approach

BioPharma Capital (BPC) offers strategic and financial advisory  services focused on creating value for emerging life science companies

Who We Are

  • Our team is passionate about maximizing value for our clients using credible scientific and evidence-driven strategies
  • We have decades of experience in transaction advisory, health care strategy consulting, pricing and market access, forecasting, investment banking, and translational research
Value
Creation

Who We Serve

  • Our clients are typically emerging pharmaceutical and biotech companies considering partnering, licensing, co-development, co-promotion, or corporate sales
  • We work with assets in all therapy areas and in all stages of development, from pre-clinical discovery to marketed products
Leadership & Team
  • 2 Senior Advisors, 3 Project Managers, 4 Analysts
  • Access to highly qualified teams as-needed via professional networks
Activities Supported
  • Licensing, Partnering, Co-Promotion, and M&A
  • Due diligence, structuring, negotiations and valuation analyses
  • Serve as outsourced or extension of internal BD team
Fee Structures
  • Our flexible fee structures align incentives and accommodate client needs

Discussions with potential partners require strategic negotiations skills, persistence, and analytical rigor

BPC offers the focus, expertise and experience to successfully navigate partnering negotiations

Negotiations

  • Lead and participate in non-confidential and confidential discussions
  • Maintain active communication with your company team and coordinate scheduling with external parties including bidders and other vendors
  • Provide guidance on term sheet valuations and counteroffers

Financial Modeling & Deal Structuring

  • Build and maintain a model to generate term sheets and create rationale for offers/counteroffers or alternate structures that accommodate different viewpoints between partners
  • Adapt NPV model as new insights on inputs are gained and use new outputs to adapt deal materials accordingly

Data room

  • Monitor data room activities as per degree of visibility defined by host site
  • Update materials to adapt to possible partner concerns

We offer services tailored specifically to biopharma deal-making that are designed to surpass both IB and consulting offerings

Transaction AdvisorRigorous, Data-Driven Life-Science Market InsightsWill go at-risk with clients to align interestsExtensive NetworksDeal brokering and execution
Investment Banks
Healthcare Consultants
BioPharma Capital

BioPharma Capital has capabilities and resources to provide strategic transaction advisory to life science companies

Strategic Advisory

An emphasis on optimizing value

BioPharma Capital, LLC has in-depth knowledge and global resources for emerging biopharma companies.

M&A

M&A Sell-Side Engagements

We can help you

  • Refine your pitch using our deep expertise in the pharmaceutical industry and understanding of what resonates with potential acquirers
  • Credibly articulate and validate your commercial opportunity by leveraging available third-party healthcare data and analytics
  • Target acquirers through our vast network in the life sciences industry

Partnering/Licensing Engagements

We can help you

  1. 01

    Refine your pitch using our deep expertise in the pharmaceutical industry and understanding of what resonates with potential partners

  2. 02

    Credibly articulate your commercial opportunity by accessing third-party healthcare data and analytics

  3. 03

    Target both global and regional partners through our vast network in the life sciences industry

  4. 04

    Structure transactions including upfront payments, milestones and royalties

  5. 05

    Negotiate and execute transactions

BPC ensures that the engagement process is well-orchestrated and runs at the proper cadence

Our process is designed to provide the most opportunities to solicit interest from the broadest possible set of potential partners and achieve the most favorable terms

PARTNERING ENGAGEMENT ACTIVITY SCHEMATICPARTNERING ENGAGEMENT ACTIVITY SCHEMATICMgmt TeamBoardNo InterestInterestNo CDAExecuted CDANo InterestInterestInterestNo InterestBlinded 2-PagerFeedback,ReviseMaterialsPropose CDAPresentationPresentationFeedback,ReviseMaterialsTerms SheetDataroomNegotiationsFeedback,ReviseMaterialsTransactionIllustrative

BPC quantifies term sheets to facilitate comparison of offers and provide guidance on counter-offers

Net increase in NPV from initial term sheet to current term sheetNet increase in NPV from initial term sheet to current term sheet$ Millions (except descriptors on x-axis)$400$450$500$550$600$650$700$526.5$23.8$7.3$68.4$6.3$15.0$15.0$619.7term sheetterritoryFTE rate+1% (alltiers)Upfront@ end ofPhase 1Milestone @start ofPhase 2Revised offerIllustrative
  • Quantification of deal terms enables a uniform comparison of offers with differing milestones and payment options
  • Our analysis forms the basis for developing counter-offers to potential partners, and a supporting rationale to use in negotiations

Case Studies

Case studies available on request

Contact Us

Financing

With BioPharma Capital you have a valued partner

We seek to understand and target the right investors that align with our clients’ objectives and management style.

A Partner to Our Clients

We raise capital for our clients to accelerate growth by

  1. 01

    Accessing our vast network of healthcare investors

  2. 02

    Helping to successfully articulate their value and potential to investors

  3. 03

    Developing independent, third-party valuation analyses leveraging the multitude of data and expertise available to BioPharma Capital to credibly support pre-money valuations

  4. 04

    Leveraging our experience to structure the financing and negotiate terms

A Resource to Strategic Partners

BioPharma Capital provides sophisticated pharma and biotech companies with unique pre-screened deal flow, offering an efficient way to identify opportunities that suit your business development objectives.

We conduct rigorous due diligence on potential opportunities, specifically screening for

  • Compelling science

  • Robust intellectual property

  • Experienced management team

  • Attractive commercial potential

  • Sound business strategy

  • Clear roadmap to value creation

Representative Transactions

Representative transactions available on request

Contact Us

Transactions

The BPC Team has supported over $13B in announced transaction value

1 / 12

Not Exhaustive

2021 RemeGen–Seagen deal was highly covered by top media outlets in the industry

SeagenRemeGen

Seagen and RemeGen Announce Exclusive Worldwide License and Co-Development Agreement for Disitamab Vedotin

08/09/2021

– Seagen Licenses Disitamab Vedotin, a Novel HER2-targeted Antibody-Drug Conjugate (ADC) from RemeGen –

– Disitamab Vedotin has Shown Potential as a Differentiated ADC Across a Range of HER2 Expressing Tumors and is Being Developed as Monotherapy and in Combination with PD-1 Inhibitors, Further Expanding and Complementing Seagen’s Deep and Diverse Pipeline –

– Agreement Leverages Seagen and RemeGen’s Leadership and Expertise in Developing ADCs as well as Seagen’s Global Development and Commercialization Capabilities –

BOTHELL, Wash. & YANTAI, China--(BUSINESS WIRE)-- Seagen Inc. (Nasdaq: SGEN), a world leader and pioneer in antibody-drug conjugate (ADC) therapies, and RemeGen Co., Ltd. (9995.HK), a leading innovative biopharmaceutical company in China, today announced that the two companies have entered into an exclusive worldwide licensing agreement to develop and commercialize disitamab vedotin, a novel HER2-targeted ADC.

Disitamab vedotin combines the drug-linker technology originally developed by Seagen with RemeGen’s novel HER2 antibody exhibiting higher affinity and an increased internalization rate as compared to trastuzumab in preclinical models.1, 2 As monotherapy, disitamab vedotin has demonstrated antitumor activity in

https://investor.seagen.com/press-releases/news-details/2021/Seagen-and-RemeGen-Announce-Exclusive-Worldwide-License-and-Co-Development-Agreement-for-Disitamab-Vedotin/default.aspx
FiercePharma

In $2.6B cancer deal, Seagen bets China's first homemade ADC can challenge Roche, AZ-Daiichi

By Angus Liu · Aug 9, 2021 10:21am

https://www.fiercepharma.com/pharma/taking-aim-at-roche-and-astra-daiichi-seagen-bets-up-to-2-6b-china-s-first-home-made-adc
BioSpace

Seagen Strikes $2.6 Billion ADC Deal with China’s RemeGen

Seagen, formerly known as Seattle Genetics, forged an exclusive licensing agreement with China’s RemeGen Co., Ltd, to develop and commercialize disitamab vedotin, a novel HER2-targeted antibody drug conjugate (ADC). The deal is valued at about $2.6 billion.

Disitamab vedotin combines the drug-linker technology developed by Seagen with RemeGen’s novel HER2 antibody.

https://www.biospace.com/article/seagen-strikes-2-6-billion-adc-deal-with-china-s-remegen/

RemeGen-Seagen was ranked as the largest out-licensing deal from China in 2021

Top 10 China Out-Licensing deals in 2021

LicenseeLicensorRegional RightAssetsDisease AreaDeal Value (US$m)
SeagenRemeGenGlobalDisitamab VedotinOncology2600
NovartisBeiGeneex-ChinatislelizumabOncology2200
LillyRegor Therapeuticsex-ChinaGLP-1RMetabolic Disease1500
FibroGenHiFiBioGlobalGalectin-9, and exclusive option for CXCR6 and CCR8Oncology1125
CoherusJunshi BiosciencesUS and CanadaToripalimabOncology1110
NovartisBeiGeneex-ChinaOciperlimab (BGB-A1217)anti-cancer therapy1000
BiogenInnoCareex-ChinaorelabrutinibAutoimmune937.5
ArriVentAllistex-ChinafurmonertinibOncology805
BeiGeneNanjing Leads Biolabsex- ChinaLBL-007 Anti-LAG-3 AntibodyOncology742
Flame BiosciencesNovaRock Biotherapeutics (Subsidiary of CSPC)ex- Greater ChinaNBL-015Oncology640

Source: “2021 China Biopharma Review”, MSQ Analytics, January 11th, 2022

BioPharma Capital Team Members

Our team is comprised of individuals with business development, licensing, investment banking, and pricing and market access expertise. We understand the science and technology behind the assets we represent and we have vast expertise managing transactions. This combination of talent and a network of connections provides our clients with exceptional service.

Dan Ross

Dan Ross

Managing Partner
BioPharma Capital, LLC

ph: +1 619 208-8439

dan@biopharmacapital.com

Current responsibility

  • Pitch, negotiate and close successful transactions on behalf of clients
  • Continue to expand professional network amongst strategic buyers and institutional investors

Profile overview

  • Experienced in several therapeutic areas
  • Expanded BD advisory relationship with RemeGen, serving as Chief Business Officer 2022-2024
  • Previously served as Chairman, President and CEO of IMS Health Capital
  • Started in health care at SalomonSmithBarney Investment Banking Division (New York / London)

Education

  • M.B.A. from Stanford University Graduate School of Business
  • Bachelor’s degree from San Diego State University

Areas of expertise

  • Deal brokering
  • Strategic advisory
  • Transaction structuring
  • Negotiations
  • Valuation

Relevant experience

  • M&A, Financing, Partnering Transactions
  • Business development strategy consulting

Any testimonial or endorsement may not be representative of the experience of other customers and is no guarantee of future performance or success.

Contact Info

BioPharma Capital, LLC

Office
La Jolla, CA
USA

Dan Ross, MBA

Role
Managing Partner
Phone
+1 619 208-8439
Email
dan@biopharmacapital.com

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